50 HUMAN SUBJECT REPEAT INSULT PATCH TEST
SKIN IRRITATION/SENSITIZATION EVALUATION
(OCCLUSIVE PATCH)

Cantor Research Laboratories, Inc.
50 HUMAN SUBJECT REPEAT INSULT PATCH TEST
SKIN IRRITATION/SENSITIZATION EVALUATION
(OCCLUSIVE PATCH)

Date:

July 21, 2005

CR Ref. No.:

RIPT.C0608-A.O.50.GLO

Sponsor:
GLOVES IN A BOTTLE, INC.
P.O. Box 615

Montrose CA 91021

1.0 Objective:

Consumer products or raw materials designed for consistent reapplication to areasof the skin may, under proper conditions, prove to be contact sensitizers or irritanta in certain individuals. It is the intention of a Repeat Insult Patch Test (RIPT) to provide a basis for evaluation of this irritation/sensitization potential if such exists.

2.0 Reference:

The method is modified to test 50 panelists and not the 200 cited in the reference Appraisal of the Safety of Chemicals in Food, Drugs and Cosmetics, published by The Association of Food and Drug Officias of the United States. The method also employs nine inductive patchings and not the ten cited in the reference.

3.0 Test Material:
3.1 Test Material Description:

On June 8, 2005 on test sample labeled Lotion, Product Code No. 7-1A was received from GLOVES IN A BOTTLE, INC. and assigned CR Lab No. C0608-A.

3.2 Handling:

Upon arrival at Cantor Research Laboratories, Inc., the test material is assigned a unique laboratory code number and entered into a daily log identifying the lot number, sample description, sponsop, date and test requested.

Samples are retained for a period of three month beyond submissions of final reports unless otherwise specified by the sponsor or, if sample is known to be in support of governmental applications, representative retained samples are kept two years beyound final report submission.

9.0 Results:

Please refer to attached Table.

10.0 Observations:

No adverse reactions of any kind were noted during the course of this study.

11.0 Archiving

All raw data sheets, technician’s notebooks, correspondence files, and copies of final reports are maintained on premises of Cantor Research Laboratories, Inc., in limited access storage files marked “Archive” for rive years after completion of the study. A duplicate disk copy of final reports is separately archived in a bank safe deposit vault.

12.0 Conclusions:

The test material (CR Lab No.: C0608-A; Client No.: Lotion, Product Code No. 7-1A) when tested under occlusive condition as described herein, may be considered as a NON-PRIMARY IRRITANT and a NON-PRIMARY SENSITIZER to the skin according to the reference.

Download:

Skin irritation (hypoallergenic) test results by Cantor Research Laboratories PDF

Cantor Research Laboratories,
Inc. ANALYTICAL REPORT

GLOVES IN A BOTTLE, INC.
P.O. Box 615
Montrose CA 91021

SAMPLE DESCRIPTION:

ACCESSION #: 38821

SAMPLE: White Lotion

LOT #: N/A

TEST PERFORMED: Human Patch Test (50 SUBJECT)

RESULTS: Human Patch Test

ACC # 38821 No evidence of sensitization


Ranil M. Fernando, B.C.
Operations Manager

Report day:
12/01/98
Date Recieved:
10/20/98
Date Completed:
12/01/98
Project #:
38821
P.O. #:
N/A
Reference #:
N/A

Download: analytical report by BioScreen Testing Services, Inc. PDF